Western blot analysis of extracts of various cell lines, using KCNIP1 antibody (STJ24294) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-KCNIP1 antibody (1-216) (STJ24294)

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STJ24294
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNIP1
Gene ID: 30820
Uniprot ID: KCIP1_HUMAN
Immunogen Region: 1-216
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human KCNIP1 (NP_055407.1).
Immunogen Sequence: MGAVMGTFSSLQTKQRRPSK DKIEDELEMTMVCHRPEGLE QLEAQTNFTKRELQVLYRGF KNECPSGVVNEDTFKQIYAQ FFPHGDASTYAHYLFNAFDT TQTGSVKFEDFVTALSILLR GTVHEKLRWTFNLYDINKDG YINKEEMMDIVKAIYDMMGK YTYPVLKEDTPRQHVDVFFQ KMDKNKDGIVTLDEFLESCQ EDDNIMRSLQLFQNVM
Tissue Specificity Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus.
Function Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.
Protein Name A-Type Potassium Channel Modulatory Protein Kcnip1
Kv Channel-Interacting Protein 1
Kchip1
Potassium Channel-Interacting Protein 1
Vesicle Apc-Binding Protein
Database Links Reactome: R-HSA-5576894
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasm
Cell Projection
Dendrite
Alternative Antibody Names Anti-A-Type Potassium Channel Modulatory Protein Kcnip1 antibody
Anti-Kv Channel-Interacting Protein 1 antibody
Anti-Kchip1 antibody
Anti-Potassium Channel-Interacting Protein 1 antibody
Anti-Vesicle Apc-Binding Protein antibody
Anti-KCNIP1 antibody
Anti-KCHIP1 antibody
Anti-VABP antibody

Information sourced from Uniprot.org

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