| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KCNA10 (1-125) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNA10 |
| Gene ID: |
3744 |
| Uniprot ID: |
KCA10_HUMAN |
| Immunogen Region: |
1-125 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human KCNA10 (NP_005540.1). |
| Immunogen Sequence: |
MDVCGWKEMEVALVNFDNSD EIQEEPGYATDFDSTSPKGR PGGSSFSNGKILISESTNHE TAFSKLPGDYADPPGPEPVV LNEGNQRVIINIAGLRFETQ LRTLSQFPETLLGDREKRMQ FFDSM |
| Tissue Specificity | Detected in kidney, in proximal tubules, glomerular endothelium, in vascular endothelium and in smooth muscle cells. |
| Function | Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP. |
| Protein Name | Potassium Voltage-Gated Channel Subfamily A Member 10Voltage-Gated Potassium Channel Subunit Kv1.8 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Voltage-Gated Channel Subfamily A Member 10 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv1.8 antibodyAnti-KCNA10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
