| Tissue Specificity | Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level). |
| Function | Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. |
| Protein Name | Kazrin |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | CytoplasmCytoskeletonIsoform 2: CytoplasmCell JunctionDesmosomeNucleusObserved At The Apical Plasma Membrane Of KeratinocytesPartially Colocalizes With Ppl And Dp At DesmosomesAnd With Pp At The Interdesmosomal Plasma MembraneColocalizes With Cortical Actin-Based Membrane StructuresIsoform 3: CytoplasmIsoform 4: Cytoplasm |
| Alternative Antibody Names | Anti-Kazrin antibodyAnti-KAZN antibodyAnti-C1orf196 antibodyAnti-KAZ antibodyAnti-KIAA1026 antibodyAnti-HRIHFB2003 antibody |
Information sourced from Uniprot.org
