| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-JPH4 (405-605) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
JPH4 |
| Gene ID: |
84502 |
| Uniprot ID: |
JPH4_HUMAN |
| Immunogen Region: |
405-605 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 405-605 of human JPH4 (NP_115828.2). |
| Immunogen Sequence: |
AARMAKLIAQDLQPMLEAPG RRPRQDSEGSDTEPLDEDSP GVYENGLTPSEGSPELPSSP ASSRQPWRPPACRSPLPPGG DQGPFSSPKAWPEEWGGAGA QAEELAGYEAEDEAGMQGPG PRDGSPLLGGCSDSSGSLRE EEGEDEEPLPPLRAPAGTEP EPIAMLVLRGSSSRGPDAGC LTEELGEPAATERPAQPGAA N |
| Function | Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory. |
| Protein Name | Junctophilin-4Jp-4Junctophilin-Like 1 Protein |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneSingle-Pass Type Iv Membrane ProteinLocalized Predominantly On The Plasma MembraneThe Transmembrane Domain Is Anchored In Endoplasmic Reticulum MembraneWhile The N-Terminal Part Associates With The Plasma Membrane |
| Alternative Antibody Names | Anti-Junctophilin-4 antibodyAnti-Jp-4 antibodyAnti-Junctophilin-Like 1 Protein antibodyAnti-JPH4 antibodyAnti-JPHL1 antibodyAnti-KIAA1831 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
