| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DCAF6 |
| Gene ID: | 55827 |
| Uniprot ID: | DCAF6_HUMAN |
| Immunogen Region: | 460-650 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 460-650 of human IQWD1 (NP_001017977.1). |
| Immunogen Sequence: | DNNNEKLSPKPGTGEPVLSL HYSTEGTTTSTIKLNFTDEW SSIASSSRGIGSHCKSEGQE ESFVPQSSVQPPEGDSETKA PEESSEDVTKYQEGVSAENP VENHINITQSDKFTAKPLDS NSGERNDLNLDRSCGVPEES ASSEKAKEPETSDQTSTESA TNENNTNPEPQFQTEATGPS AHEETSTRDSA |
| Tissue Specificity | Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland. |
| Function | Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. |
| Protein Name | Ddb1- And Cul4-Associated Factor 6Androgen Receptor Complex-Associated ProteinArcapIq Motif And Wd Repeat-Containing Protein 1Nuclear Receptor Interaction ProteinNrip |
| Database Links | Reactome: R-HSA-8951664 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ddb1- And Cul4-Associated Factor 6 antibodyAnti-Androgen Receptor Complex-Associated Protein antibodyAnti-Arcap antibodyAnti-Iq Motif And Wd Repeat-Containing Protein 1 antibodyAnti-Nuclear Receptor Interaction Protein antibodyAnti-Nrip antibodyAnti-DCAF6 antibodyAnti-IQWD1 antibodyAnti-MSTP055 antibody |
Information sourced from Uniprot.org