| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IMP3 |
| Gene ID: |
55272 |
| Uniprot ID: |
IMP3_HUMAN |
| Immunogen Region: |
1-184 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human IMP3 (NP_060755.1). |
| Immunogen Sequence: |
MVRKLKFHEQKLLKQVDFLN WEVTDHNLHELRVLRRYRLQ RREDYTRYNQLSRAVRELAR RLRDLPERDQFRVRASAALL DKLYALGLVPTRGSLELCDF VTASSFCRRRLPTVLLKLRM AQHLQAAVAFVEQGHVRVGP DVVTDPAFLVTRSMEDFVTW VDSSKIKRHVLEYNEERDDF DLEA |
| Function | Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | U3 Small Nucleolar Ribonucleoprotein Protein Imp3U3 Snornp Protein Imp3Brms2 |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-U3 Small Nucleolar Ribonucleoprotein Protein Imp3 antibodyAnti-U3 Snornp Protein Imp3 antibodyAnti-Brms2 antibodyAnti-IMP3 antibodyAnti-C15orf12 antibodyAnti-MRPS4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
