| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Icam5 |
| Gene ID: | 15898 |
| Uniprot ID: | ICAM5_MOUSE |
| Immunogen Region: | 586-786 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 586-786 of mouse Icam5 (NP_032345.2). |
| Immunogen Sequence: | VEGSGKLFSCEVDGKPEPRV ECVGSEGASEGIVLPLVSSN SGPRNSMTPGNLSPGIYLCN ATNRHGSTVKTVVVSAESPP QMDESSCPSHQTWLEGAEAT ALACSARGRPSPRVHCSREG AARLERLQVSREDAGTYRCV ATNAHGTDSRTVTVGVEYRP VVAELAASPPSVRPGGNFTL TCRAEAWPPAQISWRAPPGA L |
| Tissue Specificity | Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon. |
| Post Translational Modifications | Glycosylation at Asn-54 is critical for functional folding. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). |
| Protein Name | Intercellular Adhesion Molecule 5Icam-5Telencephalin |
| Database Links | Reactome: R-MMU-198933Reactome: -MMU-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 5 antibodyAnti-Icam-5 antibodyAnti-Telencephalin antibodyAnti-Icam5 antibodyAnti-Icam3 antibodyAnti-Tlcn antibody |
Information sourced from Uniprot.org