Western blot analysis of various lysates, using HSD17B2 antibody (STJ24083) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 0. 1s.

Anti-HSD17B2 antibody (100-387) (STJ24083)

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STJ24083
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HSD17B2
Gene ID: 3294
Uniprot ID: DHB2_HUMAN
Immunogen Region: 100-387
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human HSD17B2 (NP_002144.1).
Immunogen Sequence: KYLDELGFTVFAGVLNENGP GAEELRRTCSPRLSVLQMDI TKPVQIKDAYSKVAAMLQDR GLWAVINNAGVLGFPTDGEL LLMTDYKQCMAVNFFGTVEV T
Tissue Specificity Expressed in placenta.
Function Catalyzes the NAD-dependent oxidation of the highly active 17beta-hydroxysteroids, such as estradiol (E2), testosterone (T), and dihydrotestosterone (DHT), to their less active forms and thus regulates the biological potency of these steroids. Oxidizes estradiol to estrone, testosterone to androstenedione, and dihydrotestosterone to 5alpha-androstan-3,17-dione. Also has 20-alpha-HSD activity.
Protein Name 17-Beta-Hydroxysteroid Dehydrogenase Type 2
17-Beta-Hsd 2
20 Alpha-Hydroxysteroid Dehydrogenase
20-Alpha-Hsd
E2dh
Estradiol 17-Beta-Dehydrogenase 2
Microsomal 17-Beta-Hydroxysteroid Dehydrogenase
Short Chain Dehydrogenase/Reductase Family 9c Member 2
Testosterone 17-Beta-Dehydrogenase
Database Links Reactome: R-HSA-193144
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-17-Beta-Hydroxysteroid Dehydrogenase Type 2 antibody
Anti-17-Beta-Hsd 2 antibody
Anti-20 Alpha-Hydroxysteroid Dehydrogenase antibody
Anti-20-Alpha-Hsd antibody
Anti-E2dh antibody
Anti-Estradiol 17-Beta-Dehydrogenase 2 antibody
Anti-Microsomal 17-Beta-Hydroxysteroid Dehydrogenase antibody
Anti-Short Chain Dehydrogenase/Reductase Family 9c Member 2 antibody
Anti-Testosterone 17-Beta-Dehydrogenase antibody
Anti-HSD17B2 antibody
Anti-EDH17B2 antibody
Anti-SDR9C2 antibody

Information sourced from Uniprot.org

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