| Tissue Specificity | Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. |
| Function | The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). |
| Protein Name | Histamine H4 ReceptorH4rHh4rAxor35G-Protein Coupled Receptor 105Gprv53Pfi-013Sp9144 |
| Database Links | Reactome: R-HSA-390650Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Histamine H4 Receptor antibodyAnti-H4r antibodyAnti-Hh4r antibodyAnti-Axor35 antibodyAnti-G-Protein Coupled Receptor 105 antibodyAnti-Gprv53 antibodyAnti-Pfi-013 antibodyAnti-Sp9144 antibodyAnti-HRH4 antibodyAnti-GPCR105 antibody |
Information sourced from Uniprot.org
