| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HEXIM2 (147-286) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HEXIM2 |
| Gene ID: |
124790 |
| Uniprot ID: |
HEXI2_HUMAN |
| Immunogen Region: |
147-286 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 147-286 of human HEXIM2 (NP_653209.1). |
| Immunogen Sequence: |
LMNDRDPEEPNLDVPHGISH PGSSGESEAGDSDGRGRAHG EFQRKDFSETYERFHTESLQ GRSKQELVRDYLELEKRLSQ AEEETRRLQQLQACTGQQSC RQVEELAAEVQRLRTENQRL RQENQMWNREGCRCDEEPGT |
| Tissue Specificity | Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed. |
| Function | Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. |
| Protein Name | Protein Hexim2Hexamethylene Bis-Acetamide-Inducible Protein 2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Hexim2 antibodyAnti-Hexamethylene Bis-Acetamide-Inducible Protein 2 antibodyAnti-HEXIM2 antibodyAnti-L3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
