| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HERC3 |
| Gene ID: | 8916 |
| Uniprot ID: | HERC3_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HERC3 (NP_055421.1). |
| Immunogen Sequence: | MLCWGYWSLGQPGISTNLQG IVAEPQVCGFISDRSVKEVA CGGNHSVFLLEDGEVYTCGL NTKGQLGHEREGNKPEQIGA LADQHIIHVACGESHSLALS DRGQLFSWGAGSDGQLGLMT TEDSVAVPRLIQKLNQQTIL QVSCGNWHCLALAADGQFFT WGKNSHGQLGLGKEFPSQAS PQRVRSLEGIPLAQVAAGGA |
| Post Translational Modifications | Ubiquitinated.which promotes degradation by the proteasome. |
| Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. |
| Protein Name | Probable E3 Ubiquitin-Protein Ligase Herc3Hect Domain And Rcc1-Like Domain-Containing Protein 3Hect-Type E3 Ubiquitin Transferase Herc3 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytoplasmic VesicleAlso Found In Vesicular-Like Structures |
| Alternative Antibody Names | Anti-Probable E3 Ubiquitin-Protein Ligase Herc3 antibodyAnti-Hect Domain And Rcc1-Like Domain-Containing Protein 3 antibodyAnti-Hect-Type E3 Ubiquitin Transferase Herc3 antibodyAnti-HERC3 antibodyAnti-KIAA0032 antibody |
Information sourced from Uniprot.org