| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HARS1 |
| Gene ID: | 3035 |
| Uniprot ID: | HARS1_HUMAN |
| Immunogen Region: | 1-180 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HARS (NP_002100.2). |
| Immunogen Sequence: | MAERAALEELVKLQGERVRG LKQQKASAELIEEEVAKLLK LKAQLGPDESKQKFVLKTPK GTRDYSPRQMAVREKVFDVI IRCFKRHGAEVIDTPVFELK ETLMGKYGEDSKLIYDLKDQ GGELLSLRYDLTVPFARYLA MNKLTNIKRYHIAKVYRRDN PAMTRGRYREFYQCDFDIAG |
| Tissue Specificity | Brain, heart, liver and kidney. |
| Function | Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Plays a role in axon guidance. |
| Protein Name | Histidine--Trna Ligase - CytoplasmicHistidyl-Trna SynthetaseHisrs |
| Database Links | Reactome: R-HSA-379716 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Histidine--Trna Ligase - Cytoplasmic antibodyAnti-Histidyl-Trna Synthetase antibodyAnti-Hisrs antibodyAnti-HARS1 antibodyAnti-HARS antibodyAnti-HRS antibody |
Information sourced from Uniprot.org