| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR119 |
| Gene ID: | 139760 |
| Uniprot ID: | GP119_HUMAN |
| Immunogen Region: | 200-300 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GPR119 (NP_848566.1). |
| Immunogen Sequence: | RKMEHAGAMAGGYRSPRTPS DFKALRTVSVLIGSFALSWT PFLITGIVQVACQECHLYLV LERYLWLLGVGNSLLNPLIY AYWQKEVRLQLYHMALGVKK V |
| Tissue Specificity | Predominantly expressed in the pancreas, especially in the islets. |
| Function | Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. |
| Protein Name | Glucose-Dependent Insulinotropic ReceptorG-Protein Coupled Receptor 119 |
| Database Links | Reactome: R-HSA-381771Reactome: R-HSA-400511 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Glucose-Dependent Insulinotropic Receptor antibodyAnti-G-Protein Coupled Receptor 119 antibodyAnti-GPR119 antibody |
Information sourced from Uniprot.org