Tissue Specificity | Expressed in the heart, whole brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
Post Translational Modifications | The alpha- and beta-subunits are generated by a proteolytic cleavage by MBTPS1 protease at the Lys-928-Asp-929 bond. |
Function | Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment. |
Protein Name | N-Acetylglucosamine-1-Phosphotransferase Subunits Alpha/BetaGlcnac-1-Phosphotransferase Subunits Alpha/BetaStealth Protein GnptabUdp-N-Acetylglucosamine-1-Phosphotransferase Subunits Alpha/Beta Cleaved Into - N-Acetylglucosamine-1-Phosphotransferase Subunit Alpha - N-Acetylglucosamine-1-Phosphotransferase Subunit Beta |
Cellular Localisation | N-Acetylglucosamine-1-Phosphotransferase Subunit Alpha: Golgi Apparatus MembraneSingle-Pass Type I Membrane ProteinN-Acetylglucosamine-1-Phosphotransferase Subunit Beta: Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-N-Acetylglucosamine-1-Phosphotransferase Subunits Alpha/Beta antibodyAnti-Glcnac-1-Phosphotransferase Subunits Alpha/Beta antibodyAnti-Stealth Protein Gnptab antibodyAnti-Udp-N-Acetylglucosamine-1-Phosphotransferase Subunits Alpha/Beta Cleaved Into - N-Acetylglucosamine-1-Phosphotransferase Subunit Alpha - N-Acetylglucosamine-1-Phosphotransferase Subunit Beta antibodyAnti-GNPTAB antibodyAnti-GNPTA antibodyAnti-KIAA1208 antibody |
Information sourced from Uniprot.org