Anti-GNPTAB antibody (42-350) (STJ118340)

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STJ118340
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GNPTAB
Gene ID: 79158
Uniprot ID: GNPTA_HUMAN
Immunogen Region: 42-350
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 42-350 of human GNPTAB (NP_077288.2).
Immunogen Sequence: LEWSRDQYHVLFDSYRDNIA GKSFQNRLCLPMPIDVVYTW VNGTDLELLKELQQVREQME EEQKAMREILGKNTTEPTKK SEKQLECLLTHCIKVPMLVL DPALPANITLKDLPSLYPSF HSASDIFNVAKPKNPSTNVS VVVFDSTKDVEDAHSGLLKG NSRQTVWRGYLTTDKEVPGL VLMQDLAFLSGFPPTFKETN QLKTKLPENLSSKVKLLQLY SEASVALLKLNNPKDFQEL
Tissue Specificity Expressed in the heart, whole brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Post Translational Modifications The alpha- and beta-subunits are generated by a proteolytic cleavage by MBTPS1 protease at the Lys-928-Asp-929 bond.
Function Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment.
Protein Name N-Acetylglucosamine-1-Phosphotransferase Subunits Alpha/Beta
Glcnac-1-Phosphotransferase Subunits Alpha/Beta
Stealth Protein Gnptab
Udp-N-Acetylglucosamine-1-Phosphotransferase Subunits Alpha/Beta Cleaved Into - N-Acetylglucosamine-1-Phosphotransferase Subunit Alpha - N-Acetylglucosamine-1-Phosphotransferase Subunit Beta
Cellular Localisation N-Acetylglucosamine-1-Phosphotransferase Subunit Alpha: Golgi Apparatus Membrane
Single-Pass Type I Membrane Protein
N-Acetylglucosamine-1-Phosphotransferase Subunit Beta: Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-N-Acetylglucosamine-1-Phosphotransferase Subunits Alpha/Beta antibody
Anti-Glcnac-1-Phosphotransferase Subunits Alpha/Beta antibody
Anti-Stealth Protein Gnptab antibody
Anti-Udp-N-Acetylglucosamine-1-Phosphotransferase Subunits Alpha/Beta Cleaved Into - N-Acetylglucosamine-1-Phosphotransferase Subunit Alpha - N-Acetylglucosamine-1-Phosphotransferase Subunit Beta antibody
Anti-GNPTAB antibody
Anti-GNPTA antibody
Anti-KIAA1208 antibody

Information sourced from Uniprot.org