Anti-GLRA3 antibody (STJA0007641)

SKU:
STJA0007641
€60.00 - €315.00
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Glycine receptor subunit alpha-3 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GLRA3
Gene ID: 8001
Uniprot ID: GLRA3_HUMAN
Specificity: This antibody detects endogenous levels of GLRA3 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human GLRA3
Post Translational Modifications Phosphorylated by PKA.this causes down-regulation of channel activity.
Function Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel characteristics depend on the subunit composition.heteropentameric channels display faster channel closure. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Contributes to increased pain perception in response to increased prostaglandin E2 levels. Plays a role in cellular responses to ethanol.
Protein Name Glycine Receptor Subunit Alpha-3
Database Links Reactome: R-HSA-112314
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Perikaryon
Cell Projection
Dendrite
Synapse
Cell Membrane
Partially Colocalizes With Gphn That Is Known To Mediate Receptor Clustering At Postsynaptic Membranes
Alternative Antibody Names Anti-Glycine Receptor Subunit Alpha-3 antibody
Anti-GLRA3 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ90000 Anti-ACR antibody (40-120 aa) (STJ90000) Rabbit Polyclonal Human/Rat/Mouse WB/IHC/IF/ELISA
STJ140213 Anti-mCherry antibody (STJ140213) Goat Polyclonal RFP/tdTomato/mCherry WB/IHC-F/IHC-P/IF/IEM
STJ140272 Anti-mMaroon antibody (STJ140272) Goat Polyclonal Far-RFP WB/IHC-F/IHC-P/IF/IEM
STJ140118 Anti-YFP antibody (STJ140118) Goat Polyclonal Transfected cells WB/IHC-F/IHC-P/IF/IEM
STJ140010 Anti-MBP antibody (STJ140010) Goat Polyclonal MBP WB
!