Anti-GLIPR1L1 antibody (STJA0004515)

SKU:
STJA0004515

Current Stock:
Host: Rabbit
Applications: WB/IHC/ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Glipr1-Like Protein 1 is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Concentration: 0.6 mg/mL
Dilution Range: WB 1:500-1:2000, IHC 1:25-1:100
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: GLIPR1L1
Gene ID: 256710
Uniprot ID: GPRL1_HUMAN
Immunogen: Fusion protein of human GLIPR1L1
Tissue Specificity Highly expressed in testis.
Post Translational Modifications N-glycosylated. N-glycosylation decreases during the transit in the caput.
Function Required for optimal fertilization at the stage of sperm-oocyte fusion, plays a role in optimizing acrosome function, the translocation of IZUMO1 during the acrosome reaction and the fertilization process. Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins to spermatozoa plasma membrane during epididymal maturation. Also component of the CD9-positive microvesicules found in the cauda region.
Protein Name Glipr1-Like Protein 1
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Acrosome
Cell Membrane
Lipid-Anchor
Gpi-Anchor
Extracellular Side
Membrane Raft
Secreted
Located In The Connecting Piece Of Elongated Spermatids And Sperm
Also Located In The Apical Region Of The Sperm Head After Sperm Capacitation
Weakly Attached To The Cell Membrane And Later Secreted Into The Extracellular Space
Located On Sperm Equatorial Segment And Neck
Associated With Epididymosomes From The Caput And Cauda Epididymis
Alternative Antibody Names Anti-Glipr1-Like Protein 1 antibody
Anti-GLIPR1L1 antibody
Anti-UNQ2972 antibody
Anti-PRO7434 antibody

Information sourced from Uniprot.org

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