| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GALR2 |
| Gene ID: | 8811 |
| Uniprot ID: | GALR2_HUMAN |
| Immunogen Region: | 50-150 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GALR2 (NP_003848.1). |
| Immunogen Sequence: | LLRGGQAVSTTNLFILNLGV ADLCFILCCVPFQATIYTLD GWVFGSLLCKAVHFLIFLTM HASSFTLAAVSLDRYLAIRY PLHSRELRTPRNALAAIGLI W |
| Tissue Specificity | Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine. |
| Function | Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)). |
| Protein Name | Galanin Receptor Type 2Gal2-RGalr-2 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Galanin Receptor Type 2 antibodyAnti-Gal2-R antibodyAnti-Galr-2 antibodyAnti-GALR2 antibodyAnti-GALNR2 antibody |
Information sourced from Uniprot.org