| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GALM (1-342) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GALM |
| Gene ID: |
130589 |
| Uniprot ID: |
GALM_HUMAN |
| Immunogen Region: |
1-342 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human GALM (NP_620156.1). |
| Immunogen Sequence: |
MASVTRAVFGELPSGGGTVE KFQLQSDLLRVDIISWGCTI TALEVKDRQGRASDVVLGFA ELEGYLQKQPYFGAVIGRVA NRIAKGTFKVDGKEYHLAIN KEPNSLHGGVRGFDKVLWTP RVLSNGVQFSRISPDGEEGY PGELKVWVTYTLDGGELIVN YRAQASQATPVNLTNHSYFN LAGQASPNINDHEVTIEADT YLPVDETLIPTGEVAPVQGT AFDLRKPVELGKHLQDFHL |
| Function | Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose. |
| Protein Name | Galactose MutarotaseAldose 1-Epimerase |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Galactose Mutarotase antibodyAnti-Aldose 1-Epimerase antibodyAnti-GALM antibodyAnti-BLOCK25 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
