• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-FXYD3 antibody (15-65 aa) (STJ196547)

SKU:
STJ196547

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FXYD domain-containing ion transport regulator 3 (15-65 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FXYD3
Gene ID: 5349
Uniprot ID: FXYD3_HUMAN
Immunogen Region: 15-65 aa
Specificity: This antibody detects endogenous levels of FXYD3 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human FXYD3 at the amino acid range 15-65
Post Translational Modifications Glutathionylated.
Function Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. Isoform 1: Decreases the apparent K+ and Na+ affinity of the sodium/potassium-transporting ATPase over a large range of membrane potentials. Isoform 2: Decreases the apparent K+ affinity of the sodium/potassium-transporting ATPase only at slightly negative and positive membrane potentials and increases the apparent Na+ affinity over a large range of membrane potentials.
Protein Name Fxyd Domain-Containing Ion Transport Regulator 3
Chloride Conductance Inducer Protein Mat-8
Mammary Tumor 8 Kda Protein
Phospholemman-Like
Sodium/Potassium-Transporting Atpase Subunit Fxyd3
Database Links Reactome: R-HSA-5578775
Reactome: R-HSA-936837
Reactome: R-HSA-9679191
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Fxyd Domain-Containing Ion Transport Regulator 3 antibody
Anti-Chloride Conductance Inducer Protein Mat-8 antibody
Anti-Mammary Tumor 8 Kda Protein antibody
Anti-Phospholemman-Like antibody
Anti-Sodium/Potassium-Transporting Atpase Subunit Fxyd3 antibody
Anti-FXYD3 antibody
Anti-MAT8 antibody
Anti-PLML antibody

Information sourced from Uniprot.org

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