Anti-FOLR2/FR-Beta antibody [SAA1933] (STJA0020361)

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STJA0020361
£341.50 - £1,447.50
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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Folate Receptor Beta is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1933
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: FOLR2
Gene ID: 2350
Uniprot ID: FOLR2_HUMAN
Post Translational Modifications N-glycosylated.
Function Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Protein Name Folate Receptor Beta
Fr-Beta
Folate Receptor 2
Folate Receptor - Fetal/Placental
Placental Folate-Binding Protein
Fbp
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-196757
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative Antibody Names Anti-Folate Receptor Beta antibody
Anti-Fr-Beta antibody
Anti-Folate Receptor 2 antibody
Anti-Folate Receptor - Fetal/Placental antibody
Anti-Placental Folate-Binding Protein antibody
Anti-Fbp antibody
Anti-FOLR2 antibody

Information sourced from Uniprot.org