• Western blot analysis of extracts of SW620 cells, using FGF19 antibody (STJ28672) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-FGF19 antibody (25-216) (STJ28672)

SKU:
STJ28672

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FGF19 (25-216) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FGF19
Gene ID: 9965
Uniprot ID: FGF19_HUMAN
Immunogen Region: 25-216
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-216 of human FGF19 (NP_005108.1).
Immunogen Sequence: LAFSDAGPHVHYGWGDPIRL RHLYTSGPHGLSSCFLRIRA DGVVDCARGQSAHSLLEIKA VALRTVAIKGVHSVRYLCMG ADGKMQGLLQYSEEDCAFEE EIRPDGYNVYRSEKHRLPVS LSSAKQRQLYKNRGFLPLSH FLPMLPMVPEEPEDLRGHLE SDMFSSPLETDSMDPFGLVT GLEAVRSPSFEK
Tissue Specificity Expressed in fetal brain, cartilage, retina, and adult gall bladder.
Function Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
Protein Name Fibroblast Growth Factor 19
Fgf-19
Database Links Reactome: R-HSA-109704
Reactome: R-HSA-1257604
Reactome: R-HSA-1307965
Reactome: R-HSA-190322
Reactome: R-HSA-2219530
Reactome: R-HSA-5654228
Reactome: R-HSA-5654712
Reactome: R-HSA-5654719
Reactome: R-HSA-5654720
Reactome: R-HSA-5654733
Reactome: R-HSA-5673001
Reactome: R-HSA-6811558
Cellular Localisation Secreted
Alternative Antibody Names Anti-Fibroblast Growth Factor 19 antibody
Anti-Fgf-19 antibody
Anti-FGF19 antibody
Anti-UNQ334 antibody
Anti-PRO533 antibody

Information sourced from Uniprot.org

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