| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FBXO25 |
| Gene ID: | 26260 |
| Uniprot ID: | FBX25_HUMAN |
| Immunogen Region: | 142-291 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 142-291 of human FBXO25 (NP_036305.2). |
| Immunogen Sequence: | WQQQLQDLQMTKQVNNGLTL SDLPLHMLNNILYRFSDGWD IITLGQVTPTLYMLSEDRQL WKKLCQYHFAEKQFCRHLIL SEKGHIEWKLMYFALQKHYP AKEQYGDTLHFCRHCSILFW KDSGHPCTAADPDSCFTPVS PQHFIDLFKF |
| Tissue Specificity | Expressed in all brain tissue observed. |
| Function | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT). |
| Protein Name | F-Box Only Protein 25 |
| Cellular Localisation | NucleusIn The NucleusAssociates With A Subnuclear Dot-Like StructureColocalized With Skp1 |
| Alternative Antibody Names | Anti-F-Box Only Protein 25 antibodyAnti-FBXO25 antibodyAnti-FBX25 antibody |
Information sourced from Uniprot.org