| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FBXL14 |
| Gene ID: | 144699 |
| Uniprot ID: | FXL14_HUMAN |
| Immunogen Region: | 1-418 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human FBXL14 (NP_689654.1). |
| Immunogen Sequence: | METHISCLFPELLAMIFGYL DVRDKGRAAQVCTAWRDAAY HKSVWRGVEAKLHLRRANPS LFPSLQARGIRRVQILSLRR SLSYVIQGMANIESLNLSGC YNLTDNGLGHAFVQEIGSLR ALNLSLCKQITDSSLGRIAQ YLKGLEVLELGGCSNITNTG LLLIAWGLQRLKSLNLRSCR HLSDVGIGHLAGMTRSAAEG CLGLEQLTLQDCQKLTDLSL KHISRGLTGLRLLNLSFCG |
| Function | Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1. |
| Protein Name | F-Box/Lrr-Repeat Protein 14F-Box And Leucine-Rich Repeat Protein 14 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-F-Box/Lrr-Repeat Protein 14 antibodyAnti-F-Box And Leucine-Rich Repeat Protein 14 antibodyAnti-FBXL14 antibodyAnti-FBL14 antibody |
Information sourced from Uniprot.org