| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
FBLN2 |
| Gene ID: |
2199 |
| Uniprot ID: |
FBLN2_HUMAN |
| Immunogen Region: |
28-300 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 28-300 of human FBLN2 (NP_001004019.1). |
| Immunogen Sequence: |
APRQDCTGVECPPLENCIEE ALEPGACCATCVQQGCACEG YQYYDCLQGGFVRGRVPAGQ SYFVDFGSTECSCPPGGGKI SCQFMLCPELPPNCIEAVVV ADSCPQCGQVGCVHAGHKYA AGHTVHLPPCRACHCPDAGG ELICYQLPGCHGNFSDAEEG DPERHYEDPYSYDQEVAEVE AATALGGEVQAGAVQAGAGG PPAALGGGSQPLSTIQAPPW PAVLPRPTAAAALGPPAPV |
| Tissue Specificity | Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary. |
| Post Translational Modifications | O-glycosylated with core 1 or possibly core 8 glycans. It is unsure if the O-glycosylation is on Thr-347 or Ser-348. |
| Function | Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN. |
| Protein Name | Fibulin-2Fibl-2 |
| Database Links | Reactome: R-HSA-2129379 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Fibulin-2 antibodyAnti-Fibl-2 antibodyAnti-FBLN2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
