| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FARS2 (1-250) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FARS2 |
| Gene ID: |
10667 |
| Uniprot ID: |
SYFM_HUMAN |
| Immunogen Region: |
1-250 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human FARS2 (NP_006558.1). |
| Immunogen Sequence: |
MVGSALRRGAHAYVYLVSKA SHISRGHQHQAWGSRPPAAE CATQRAPGSVVELLGKSYPQ DDHSNLTRKVLTRVGRNLHN QQHHPLWLIKERVKEHFYKQ YVGRFGTPLFSVYDNLSPVV TTWQNFDSLLIPADHPSRKK GDNYYLNRTHMLRAHTSAHQ WDLLHAGLDAFLVVGDVYRR DQIDSQHYPIFHQLEAVRLF SKHELFAGIKDGESLQLFEQ SSRSAHKQETHTMEAVKLV |
| Function | Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins. |
| Protein Name | Phenylalanine--Trna Ligase - MitochondrialPhenylalanyl-Trna SynthetasePhers |
| Database Links | Reactome: R-HSA-379726 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion |
| Alternative Antibody Names | Anti-Phenylalanine--Trna Ligase - Mitochondrial antibodyAnti-Phenylalanyl-Trna Synthetase antibodyAnti-Phers antibodyAnti-FARS2 antibodyAnti-FARS1 antibodyAnti-HSPC320 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
