| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FAIM2 (1-105) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FAIM2 |
| Gene ID: |
23017 |
| Uniprot ID: |
LFG2_HUMAN |
| Immunogen Region: |
1-105 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human FAIM2 (NP_036438.2). |
| Immunogen Sequence: |
MTQGKLSVANKAPGTEGQQQ VHGEKKEAPAVPSAPPSYEE ATSGEGMKAGAFPPAPTAVP LHPSWAYVDPSSSSSYDNGF PTGDHELFTTFSWDDQKVRR VFVRK |
| Tissue Specificity | Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus. |
| Function | Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. |
| Protein Name | Protein Lifeguard 2Fas Apoptotic Inhibitory Molecule 2Neural Membrane Protein 35Transmembrane Bax Inhibitor Motif-Containing Protein 2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMembrane RaftPostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Protein Lifeguard 2 antibodyAnti-Fas Apoptotic Inhibitory Molecule 2 antibodyAnti-Neural Membrane Protein 35 antibodyAnti-Transmembrane Bax Inhibitor Motif-Containing Protein 2 antibodyAnti-FAIM2 antibodyAnti-KIAA0950 antibodyAnti-LFG antibodyAnti-LFG2 antibodyAnti-NMP35 antibodyAnti-TMBIM2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
