• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ETV4 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-ETV4 antibody (281-330 aa) (STJ95021)

SKU:
STJ95021

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ETS translocation variant 4 (281-330 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ETV4
Gene ID: 2118
Uniprot ID: ETV4_HUMAN
Immunogen Region: 281-330 aa
Specificity: PEA3 Polyclonal Antibody detects endogenous levels of PEA3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ETV4 at the amino acid range 281-330
Post Translational Modifications Sumoylated.enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2.
Function Transcriptional activator. May play a role in keratinocyte differentiation. (Microbial infection) Binds to the enhancer of the adenovirus E1A gene and acts as a transcriptional activator.the core-binding sequence is 5'-ACGGAATGT-3'.
Protein Name Ets Translocation Variant 4
Adenovirus E1a Enhancer-Binding Protein
E1a-F
Polyomavirus Enhancer Activator 3 Homolog
Protein Pea3
Database Links Reactome: R-HSA-5687128
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Ets Translocation Variant 4 antibody
Anti-Adenovirus E1a Enhancer-Binding Protein antibody
Anti-E1a-F antibody
Anti-Polyomavirus Enhancer Activator 3 Homolog antibody
Anti-Protein Pea3 antibody
Anti-ETV4 antibody
Anti-E1AF antibody
Anti-PEA3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance