• Western blot analysis of various lysates using FAM62B Rabbit polyclonal antibody (STJ114699) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-ESYT2 antibody (630-760) (STJ114699)

SKU:
STJ114699

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FAM62B (630-760) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ESYT2
Gene ID: 57488
Uniprot ID: ESYT2_HUMAN
Immunogen Region: 630-760
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1).
Immunogen Sequence: EKRERPPDHQHSAQVKRPSV SKEGRKTSIKSHMSGSPGPG GSNTAPSTPVIGGSDKPGME EKAQPPEAGPQGLHDLGRSS SSLLASPGHISVKEPTPSIA SDISLPIATQELRQRLRQLE NGTTLGQSPLG
Tissue Specificity Widely expressed with high level in cerebellum.
Function Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding.this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS).
Protein Name Extended Synaptotagmin-2
E-Syt2
Chr2syt
Database Links Reactome: R-HSA-1660662
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Localizes To Endoplasmic Reticulum-Plasma Membrane Contact Sites (Epcs)
Recruited To The Cell Membrane Via The Third C2 Domain
Alternative Antibody Names Anti-Extended Synaptotagmin-2 antibody
Anti-E-Syt2 antibody
Anti-Chr2syt antibody
Anti-ESYT2 antibody
Anti-FAM62B antibody
Anti-KIAA1228 antibody

Information sourced from Uniprot.org

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