Anti-EPT1 antibody (STJA0004749)

SKU:
STJA0004749

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ethanolaminephosphotransferase 1 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.1% sodium azide, 50% glycerol, pH 7.4
Purification: Antigen Affinity Purification
Concentration: 1mg/mL
Dilution Range: WB: 1:1000-2000; IP: 3ug/sample; IF: 1:100-200
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: SELENOI
Gene ID: 85465
Uniprot ID: EPT1_HUMAN
Immunogen: Recombinant human EPT1 protein expressed by E.coli
Tissue Specificity Widely expressed. Abundant in brain, placenta, liver and pancreas, followed by heart, skeletal muscle, lung and kidney. In brain it is strongly expressed in cerebellum, followed by the occipital pole and the frontal lobe.
Function Ethanolaminephosphotransferase that catalyzes the transfer of phosphoethanolamine/PE from CDP-ethanolamine to lipid acceptors, the final step in the synthesis of PE via the 'Kennedy' pathway. PE is the second most abundant phospholipid of membranes in mammals and is involved in various membrane-related cellular processes. The enzyme is critical for the synthesis of several PE species and could also catalyze the synthesis of ether-linked phospholipids like plasmanyl- and plasmenyl-PE which could explain it is required for proper myelination and neurodevelopment.
Protein Name Ethanolaminephosphotransferase 1
Hept1
Selenoprotein I
Seli
Database Links Reactome: R-HSA-1483213
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Ethanolaminephosphotransferase 1 antibody
Anti-Hept1 antibody
Anti-Selenoprotein I antibody
Anti-Seli antibody
Anti-SELENOI antibody
Anti-EPT1 antibody
Anti-KIAA1724 antibody
Anti-SELI antibody

Information sourced from Uniprot.org

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