Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Epidermal growth factor receptor kinase substrate 8-like protein 2 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:40000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | EPS8L2 |
Gene ID: | 64787 |
Uniprot ID: | ES8L2_HUMAN |
Immunogen Region: | 1-50 aa |
Specificity: | Eps8L2 Polyclonal Antibody detects endogenous levels of Eps8L2 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human ES8L2 at the amino acid range 1-50 |
Function | Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells. |
Protein Name | Epidermal Growth Factor Receptor Kinase Substrate 8-Like Protein 2 Eps8-Like Protein 2 Epidermal Growth Factor Receptor Pathway Substrate 8-Related Protein 2 Eps8-Related Protein 2 |
Database Links | Reactome: R-HSA-9662360 Reactome: R-HSA-9662361 |
Cellular Localisation | Cytoplasm Cell Projection Stereocilium Localizes At The Tips Of The Stereocilia Of The Inner And Outer Hair Cells |
Alternative Antibody Names | Anti-Epidermal Growth Factor Receptor Kinase Substrate 8-Like Protein 2 antibody Anti-Eps8-Like Protein 2 antibody Anti-Epidermal Growth Factor Receptor Pathway Substrate 8-Related Protein 2 antibody Anti-Eps8-Related Protein 2 antibody Anti-EPS8L2 antibody Anti-EPS8R2 antibody Anti-PP13181 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance