• Western blot analysis of lysates from wild type (WT) and EIF4G2/p97 knockout (KO) 293T cells, using [KO Validated] EIF4G2/p97 Rabbit polyclonal antibody (STJ11100866) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.

Anti-EIF4G2 antibody (733-850) (STJ11100866)

SKU:
STJ11100866

£212.50 - £501.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EIF4G2 (733-850) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EIF4G2
Gene ID: 1982
Uniprot ID: IF4G2_HUMAN
Immunogen Region: 733-850
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 733-850 of human EIF4G2/p97 (NP_001409.3).
Immunogen Sequence: LEKELLKQIKLDPSPQTIYK WIKDNISPKLHVDKGFVNIL MTSFLQYISSEVNPPSDETD SSSAPSKEQLEQEKQLLLSF KPVMQKFLHDHVDLQVSALY ALQVHCYNSNFPKGMLLR
Tissue Specificity Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney.
Post Translational Modifications Phosphorylation.hyperphosphorylated during mitosis.
Function Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
Protein Name Eukaryotic Translation Initiation Factor 4 Gamma 2
Eif-4-Gamma 2
Eif-4g 2
Eif4g 2
Death-Associated Protein 5
Dap-5
P97
Database Links Reactome: R-HSA-1169408
Alternative Antibody Names Anti-Eukaryotic Translation Initiation Factor 4 Gamma 2 antibody
Anti-Eif-4-Gamma 2 antibody
Anti-Eif-4g 2 antibody
Anti-Eif4g 2 antibody
Anti-Death-Associated Protein 5 antibody
Anti-Dap-5 antibody
Anti-P97 antibody
Anti-EIF4G2 antibody
Anti-DAP5 antibody
Anti-OK antibody
Anti-SW-cl.75 antibody

Information sourced from Uniprot.org

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