| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | Egf |
| Gene ID: | 13645 |
| Uniprot ID: | EGF_MOUSE |
| Immunogen Region: | 977-1029 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 977-1029 of mouse EGF (NP_034243.2). |
| Immunogen Sequence: | NSYPGCPSSYDGYCLNGGVC MHIESLDSYTCNCVIGYSGD RCQTRDLRWWELR |
| Function | EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. |
| Protein Name | Pro-Epidermal Growth FactorEgf Cleaved Into - Epidermal Growth Factor |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-1227986Reactome: -MMU-1236394Reactome: -MMU-1250196Reactome: -MMU-1257604Reactome: -MMU-177929Reactome: -MMU-179812Reactome: -MMU-180292Reactome: -MMU-180336Reactome: -MMU-182971Reactome: -MMU-1963642Reactome: -MMU-212718Reactome: -MMU-5673001Reactome: -MMU-6785631Reactome: -MMU-6811558Reactome: -MMU-8847993Reactome: -MMU-8856825Reactome: -MMU-8856828Reactome: -MMU-8863795Reactome: -MMU-9009391Reactome: -MMU-9013507 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Pro-Epidermal Growth Factor antibodyAnti-Egf Cleaved Into - Epidermal Growth Factor antibodyAnti-Egf antibody |
Information sourced from Uniprot.org