• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EFNB3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from SKOV3 cells, using EFNB3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of SKOV3 cells using Ephrin-B3 Polyclonal Antibody

Anti-EFNB3 antibody (221-270 aa) (STJ92961)

SKU:
STJ92961

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ephrin-B3 (221-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EFNB3
Gene ID: 1949
Uniprot ID: EFNB3_HUMAN
Immunogen Region: 221-270 aa
Specificity: Ephrin-B3 Polyclonal Antibody detects endogenous levels of Ephrin-B3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human EFNB3 at the amino acid range 221-270
Function Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. (Microbial infection) Acts as a receptor for nipah virus and hendra virus.
Protein Name Ephrin-B3
Eph-Related Receptor Transmembrane Ligand Elk-L3
Eph-Related Receptor Tyrosine Kinase Ligand 8
Lerk-8
Database Links Reactome: R-HSA-2682334
Reactome: R-HSA-3928662
Reactome: R-HSA-3928664
Reactome: R-HSA-3928665
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Ephrin-B3 antibody
Anti-Eph-Related Receptor Transmembrane Ligand Elk-L3 antibody
Anti-Eph-Related Receptor Tyrosine Kinase Ligand 8 antibody
Anti-Lerk-8 antibody
Anti-EFNB3 antibody
Anti-EPLG8 antibody
Anti-LERK8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance