Host: | Goat |
Applications: | WB/IHC-F/IF |
Reactivity: | Human/Rat/Mouse/Monkey/Canine |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-Early Endosome antigen 1 (1230aa C-Term) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
Purification: | This antibody is epitope-affinity purified from goat antiserum. |
Concentration: | 3 mg/mL |
Dilution Range: | WB 1:250-1:1000IF 1:25-1:250IHC-F 1:100-1:500Ferreira JV Soares AR Ramalho J et al. Sci Adv 2022 Mar PMID: 35333565Ernst K Landenberger M Nieland J et al. Toxins-Basel 2021 May PMID: 34071730 |
Storage Instruction: | For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in-20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours. |
Gene Symbol: | EEA1 |
Gene ID: | 8411 |
Uniprot ID: | EEA1_HUMAN |
Immunogen Region: | 1230aa C-Term |
Accession Number: | ENSG00000102189 |
Specificity: | Detects a band of 180 kDa by Western blot in the following human, mouse and rat whole cell lysates. |
Immunogen: | Purified recombinant peptide within residues 1230 aa to the C-terminus of human EEA1 produced in E. coli. |
Immunogen Sequence: | KKHEENEAKLTMQITALNEN LGTVKKEWQSSQRRVSELEK QTDDLRGEIAVLEATVQNNQ DERRALLERCLKGEGEIEKL QTKVLELQRKLDNTTAAVQE LGRENQSLQIKHTQALNRKW AEDNEVQNCMACGKGFSVTV RRHHCRQCGNIFCAECSAKN ALTPSSKKPVRVCDACFNDL QG |
Function | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. |
Protein Name | Early Endosome Antigen 1Endosome-Associated Protein P162Zinc Finger Fyve Domain-Containing Protein 2 |
Database Links | Reactome: R-HSA-168138 |
Cellular Localisation | CytoplasmEarly Endosome MembranePeripheral Membrane Protein |
Alternative Antibody Names | Anti-Early Endosome Antigen 1 antibodyAnti-Endosome-Associated Protein P162 antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 2 antibodyAnti-EEA1 antibodyAnti-ZFYVE2 antibody |
Information sourced from Uniprot.org