| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EDN3 |
| Gene ID: | 1908 |
| Uniprot ID: | EDN3_HUMAN |
| Immunogen Region: | 17-187 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-187 of human EDN3 (NP_996917.1). |
| Immunogen Sequence: | AGFVPCSQSGDAGRRGVSQA PTAARSEGDCEETVAGPGEE TVAGPGEGTVAPTALQGPSP GSPGQEQAAEGAPEHHRSRR CTCFTYKDKECVYYCHLDII WINTPEQTVPYGLSNYRGSF RGKRSAGPLPGNLQLSHRPH LRCACVGRYDKACLHFCTQT LDVSSNSRTAE |
| Tissue Specificity | Expressed in trophoblasts and placental stem villi vessels, but not in cultured placental smooth muscle cells. |
| Function | Endothelins are endothelium-derived vasoconstrictor peptides. |
| Protein Name | Endothelin-3Et-3Preproendothelin-3Ppet3 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476Reactome: R-HSA-9856649 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Endothelin-3 antibodyAnti-Et-3 antibodyAnti-Preproendothelin-3 antibodyAnti-Ppet3 antibodyAnti-EDN3 antibody |
Information sourced from Uniprot.org