Host: | Goat |
Applications: | Pep-ELISA/IHC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-EDG3 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000. IHC: In paraffin embedded Human Kidney shows membrane staining in CT. Recommended concentration, 2-4µg/ml. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | S1PR3 |
Gene ID: | 1903 |
Uniprot ID: | S1PR3_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_005217.2 |
Immunogen Sequence: | SSRKVANHNNSERS |
Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
Protein Name | Sphingosine 1-Phosphate Receptor 3 S1p Receptor 3 S1p3 Endothelial Differentiation G-Protein Coupled Receptor 3 Sphingosine 1-Phosphate Receptor Edg-3 S1p Receptor Edg-3 |
Database Links | Reactome: R-HSA-418594 Reactome: R-HSA-419408 Reactome: R-HSA-9009391 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 3 antibody Anti-S1p Receptor 3 antibody Anti-S1p3 antibody Anti-Endothelial Differentiation G-Protein Coupled Receptor 3 antibody Anti-Sphingosine 1-Phosphate Receptor Edg-3 antibody Anti-S1p Receptor Edg-3 antibody Anti-S1PR3 antibody Anti-C9orf108 antibody Anti-C9orf47 antibody Anti-EDG3 antibody |
Information sourced from Uniprot.org