| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DZIP3 |
| Gene ID: | 9666 |
| Uniprot ID: | DZIP3_HUMAN |
| Immunogen Region: | 1-230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human DZIP3 (NP_055463.1). |
| Immunogen Sequence: | MDSLPDEFFVRHPAVEDQRK EETENKLEKSSGQLNKQEND IPTDLVPVNLLLEVKKLLNA INTLPKGVVPHIKKFLQEDF SFQTMQREVAANSQNGEEIV PALTLRFLITQLEAALRNIQ AGNYTAHQINIGYYLTLLFL YGVALTERGKKEDYTEAENK FLVMKMMIQENEICENFMSL VYFGRGLLRCAQKRYNGGLL EFHKSLQEIGDKNDHWFDID PTEDEDLPTT |
| Tissue Specificity | Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas. |
| Function | E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA. |
| Protein Name | E3 Ubiquitin-Protein Ligase Dzip3Daz-Interacting Protein 3Ring-Type E3 Ubiquitin Transferase Dzip3Rna-Binding Ubiquitin Ligase Of 138 KdaHrul138 |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Dzip3 antibodyAnti-Daz-Interacting Protein 3 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Dzip3 antibodyAnti-Rna-Binding Ubiquitin Ligase Of 138 Kda antibodyAnti-Hrul138 antibodyAnti-DZIP3 antibodyAnti-KIAA0675 antibody |
Information sourced from Uniprot.org