| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DRAM1 |
| Gene ID: | 55332 |
| Uniprot ID: | DRAM1_HUMAN |
| Immunogen Region: | 100-200 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRAM1 (NP_060840.2). |
| Immunogen Sequence: | GLVGCFGMGIVANFQELAVP VVHDGGALLAFVCGVVYTLL QSIISYKSCPQWNSLSTCHI RMVISAVSCAAVIPMIVCAS LISITKLEWNPREKDYVYHV V |
| Function | Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy. |
| Protein Name | Dna Damage-Regulated Autophagy Modulator Protein 1Damage-Regulated Autophagy Modulator |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Dna Damage-Regulated Autophagy Modulator Protein 1 antibodyAnti-Damage-Regulated Autophagy Modulator antibodyAnti-DRAM1 antibodyAnti-DRAM antibody |
Information sourced from Uniprot.org