| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DHRS1 |
| Gene ID: | 115817 |
| Uniprot ID: | DHRS1_HUMAN |
| Immunogen Region: | 1-262 |
| Specificity: | Recombinant Protein corresponding to a sequence within amino acids 1-262 of human DHRS1 (NP_001129522.1). |
| Immunogen Sequence: | MAAPMNGQVCVVTGASRGIG RGIALQLCKAGATVYITGRH LDTLRVVAQEAQSLGGQCVP VVCDSSQESEVRSLFEQVDR EQQGRLDVLVNNAYAGVQTI LNTRNKAFWETPASMWDDIN NVGLRGHYFCSVYGARLMVP AGQGLIVVISSPGSLQYMFN VPYGVGKAACDKLAADCAHE LRRHGVSCVSLWPGIVQTEL LKEHMAKEEVLQDPVLKQFK SAFSSAETTELSGKCVVAL |
| Tissue Specificity | Detected in heart, liver, adrenal glands, and at low levels in skeletal muscle, kidney, pancreas and brain. |
| Function | NADPH-dependent oxidoreductase which catalyzes the reduction of steroids (estrone, androstene-3,17-dione and cortisone) as well as prostaglandin E1, isatin and xenobiotics in vitro. May have a role in steroid and/or xenobiotic metabolism. |
| Protein Name | Dehydrogenase/Reductase Sdr Family Member 1Short Chain Dehydrogenase/Reductase Family 19c Member 1Protein Sdr19c1 |
| Cellular Localisation | Endoplasmic ReticulumMay Be Attached To The Er Membrane By Its C-Terminus Segment |
| Alternative Antibody Names | Anti-Dehydrogenase/Reductase Sdr Family Member 1 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 19c Member 1 antibodyAnti-Protein Sdr19c1 antibodyAnti-DHRS1 antibodyAnti-SDR19C1 antibody |
Information sourced from Uniprot.org