Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-DDI1 (97-396) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DDI1 |
Gene ID: |
414301 |
Uniprot ID: |
DDI1_HUMAN |
Immunogen Region: |
97-396 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 97-396 of human DDI1 (NP_001001711.1). |
Immunogen Sequence: |
SGIAVPGTSSSRPQHPGQQQ QRTPAAQRSQGLASGEKVAG LQGLGSPALIRSMLLSNPHD LSLLKERNPPLAEALLSGSL ETFSQVLMEQQREKALREQE RLRLYTADPLDREAQAKIEE EIRQQNIEENMNIAIEEAPE SFGQVTMLYINCKVNGHPLK AFVDSGAQMTIMSQACAERC NIMRLVDRRWAGVAKGVGTQ RIIGRVHLAQIQIEGDFLQC SFSILEDQPMDMLLGLDML |
Function | Probable aspartic protease (Probable). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 (Probable). Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity. |
Protein Name | Protein Ddi1 Homolog 1 |
Alternative Antibody Names | Anti-Protein Ddi1 Homolog 1 antibodyAnti-DDI1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance