Anti-Cytokeratin 5 antibody [XM26] (STJ16101722)

Anti-Cytokeratin 5 antibody [XM26] (STJ16101722)

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STJ16101722-1
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Short Description :Mouse monoclonal anti-Cytokeratin 5 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :XM26
Isotype:IgG1k
Conjugation:Unconjugated
Concentration:>=21 mg/L
Dilution Range:IHC-P 1:100
Formulation:Tissue culture supernatant with Sodium azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Immunogen:Prokaryotic recombinant fusion protein corresponding to a 103 amino acid portion of the C-terminal region of the human cytokeratin 5 molecule.
Background Cytokeratins are a large family of cytoskeletal proteins found in epithelial cells. They are co-ordinately synthesized in pairs so that at least one member of each family is expressed in each epithelial cell. Cytokeratins assemble into obligatory heteropolymers composed of type I (acidic) and type II (basic) polypeptides to form higher order tetramers and protofilaments. Basal cells of human epidermis express acidic keratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58 kD protein that is closely related to cytokeratin 6. Point mutations in the cytokeratin 5 gene at locus 12q11-q13 can cause various types of epidermolysis bullosa simplex. Cytokeratin 5 is also reported to be expressed in most epithelial and biphasic mesotheliomas. Clone XM26 is specific for the 58 kD intermediate filament protein known as cytokeratin 5. It is not cross-reactive with cytokeratin 6.

Information sourced from Uniprot.org

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