| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CXCL14 |
| Gene ID: | 9547 |
| Uniprot ID: | CXL14_HUMAN |
| Immunogen Region: | 35-111 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-111 of human CXCL14 (NP_004878.2). |
| Immunogen Sequence: | SKCKCSRKGPKIRYSDVKKL EMKPKYPHCEEKMVIITTKS VSRYRGQEHCLHPKLQSTKR FIKWYNAWNEKRRVYEE |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes. |
| Post Translational Modifications | Ubiquitinated, followed by degradation by the proteasome. |
| Function | Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. |
| Protein Name | C-X-C Motif Chemokine 14 Chemokine Brak Mip-2g Small-Inducible Cytokine B14 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-X-C Motif Chemokine 14 antibody Anti-Chemokine Brak antibody Anti-Mip-2g antibody Anti-Small-Inducible Cytokine B14 antibody Anti-CXCL14 antibody Anti-MIP2G antibody Anti-NJAC antibody Anti-SCYB14 antibody Anti-PSEC0212 antibody Anti-UNQ240 antibody Anti-PRO273 antibody |
Information sourced from Uniprot.org