| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-CUE domain-containing protein 2 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CUEDC2 |
| Gene ID: | 79004 |
| Uniprot ID: | CUED2_HUMAN |
| Specificity: | This antibody detects endogenous levels of CUEDC2 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human CUEDC2 |
| Function | Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. |
| Protein Name | Cue Domain-Containing Protein 2 |
| Cellular Localisation | Cytoplasm Nucleus |
| Alternative Antibody Names | Anti-Cue Domain-Containing Protein 2 antibody Anti-CUEDC2 antibody Anti-C10orf66 antibody Anti-HOYS6 antibody |
Information sourced from Uniprot.org