| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPN1 |
| Gene ID: | 1369 |
| Uniprot ID: | CBPN_HUMAN |
| Immunogen Region: | 209-458 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 209-458 of human CPN1 (NP_001299.1). |
| Immunogen Sequence: | FVLSANLHGGAVVANYPYDK SFEHRVRGVRRTASTPTPDD KLFQKLAKVYSYAHGWMFQG WNCGDYFPDGITNGASWYSL SKGMQDFNYLHTNCFEITLE LSCDKFPPEEELQREWLGNR EALIQFLEQVHQGIKGMVLD ENYNNLANAVISVSGINHDV TSGDHGDYFRLLLPGIYTVS ATAPGYDPETVTVTVGPAEP TLVNFHLKRSIPQVSPVRRA PSRRHGVRAKVQPQARKKE |
| Tissue Specificity | Synthesized in the liver and secreted in plasma. |
| Function | Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation. |
| Protein Name | Carboxypeptidase N Catalytic ChainCpnAnaphylatoxin InactivatorArginine CarboxypeptidaseCarboxypeptidase N Polypeptide 1Carboxypeptidase N Small SubunitKininase-1Lysine CarboxypeptidasePlasma Carboxypeptidase BSerum Carboxypeptidase NScpn |
| Database Links | Reactome: R-HSA-977606 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Carboxypeptidase N Catalytic Chain antibodyAnti-Cpn antibodyAnti-Anaphylatoxin Inactivator antibodyAnti-Arginine Carboxypeptidase antibodyAnti-Carboxypeptidase N Polypeptide 1 antibodyAnti-Carboxypeptidase N Small Subunit antibodyAnti-Kininase-1 antibodyAnti-Lysine Carboxypeptidase antibodyAnti-Plasma Carboxypeptidase B antibodyAnti-Serum Carboxypeptidase N antibodyAnti-Scpn antibodyAnti-CPN1 antibodyAnti-ACBP antibody |
Information sourced from Uniprot.org