• Immunohistochemistry analysis of paraffin-embedded human prostate using COLEC11 antibody (STJ26983) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded rat brain using COLEC11 antibody (STJ26983) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of Mouse liver, using COLEC11 antibody (STJ26983) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-COLEC11 antibody (26-271) (STJ26983)

SKU:
STJ26983

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-COLEC11 (26-271) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COLEC11
Gene ID: 78989
Uniprot ID: COL11_HUMAN
Immunogen Region: 26-271
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-271 of human COLEC11 (NP_076932.1).
Immunogen Sequence: QPAGDDACSVQILVPGLKGD AGEKGDKGAPGRPGRVGPTG EKGDMGDKGQKGSVGRHGKI GPIGSKGEKGDSGDIGPPGP NGEPGLPCECSQLRKAIGEM DNQVSQLTSELKFIKNAVAG VRETESKIYLLVKEEKRYAD AQLSCQGRGGTLSMPKDEAA NGLMAAYLAQAGLARVFIGI NDLEKEGAFVYSDHSPMRTF NKWRSGEPNNAYDEEDCVEM VASGGWNDVACHTTMYFMC
Tissue Specificity Ubiquitous. Detected in adrenal gland, kidney, liver, ovaries and testis (at protein level).
Function Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis.
Protein Name Collectin-11
Collectin Kidney Protein 1
Cl-K1
Database Links Reactome: R-HSA-166662
Reactome: R-HSA-166663
Reactome: R-HSA-3000480
Cellular Localisation Secreted
Alternative Antibody Names Anti-Collectin-11 antibody
Anti-Collectin Kidney Protein 1 antibody
Anti-Cl-K1 antibody
Anti-COLEC11 antibody
Anti-UNQ596 antibody
Anti-PRO1182 antibody

Information sourced from Uniprot.org

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