| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Coilin (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S9MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
COIL |
| Gene ID: |
8161 |
| Uniprot ID: |
COIL_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Coilin (P38432). |
| Immunogen Sequence: |
MAASETVRLRLQFDYPPPAT PHCTAFWLLVDLNRCRVVTD LISLIRQRFGFSSGAFLGLY LEGGLLPPAESARLVRDNDC LRVKLEERGVAENSVVISNG |
| Tissue Specificity | Found in all the cell types examined. |
| Post Translational Modifications | Symmetrical dimethylation of arginine residues within the RG repeat region enhances affinity for SMN, and thus localization of SMN complexes to CBs. Phosphorylation during mitosis is associated with disassembly of CBs. |
| Function | Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs. |
| Protein Name | CoilinP80-Coilin |
| Cellular Localisation | NucleusCajal Body |
| Alternative Antibody Names | Anti-Coilin antibodyAnti-P80-Coilin antibodyAnti-COIL antibodyAnti-CLN80 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
