| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-cGMP-gated cation channel alpha-1 (401-450 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:40000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CNGA1 |
| Gene ID: |
1259 |
| Uniprot ID: |
CNGA1_HUMAN |
| Immunogen Region: |
401-450 aa |
| Specificity: |
CNG-1 Polyclonal Antibody detects endogenous levels of CNG-1 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human CNGA1 at the amino acid range 401-450 |
| Function | Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential. |
| Protein Name | Cgmp-Gated Cation Channel Alpha-1Cyclic Nucleotide-Gated Cation Channel 1Cyclic Nucleotide-Gated Channel Alpha-1Cng Channel Alpha-1Cng-1Cng1Cyclic Nucleotide-Gated Channel - PhotoreceptorRod Photoreceptor Cgmp-Gated Channel Subunit Alpha |
| Database Links | Reactome: R-HSA-2485179Reactome: R-HSA-2514859 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cgmp-Gated Cation Channel Alpha-1 antibodyAnti-Cyclic Nucleotide-Gated Cation Channel 1 antibodyAnti-Cyclic Nucleotide-Gated Channel Alpha-1 antibodyAnti-Cng Channel Alpha-1 antibodyAnti-Cng-1 antibodyAnti-Cng1 antibodyAnti-Cyclic Nucleotide-Gated Channel - Photoreceptor antibodyAnti-Rod Photoreceptor Cgmp-Gated Channel Subunit Alpha antibodyAnti-CNGA1 antibodyAnti-CNCG antibodyAnti-CNCG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
