| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CHST11 (38-352) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CHST11 |
| Gene ID: |
50515 |
| Uniprot ID: |
CHSTB_HUMAN |
| Immunogen Region: |
38-352 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 38-352 of human CHST11 (NP_060883.1). |
| Immunogen Sequence: |
HPVMRRNPFGVDICCRKGSR SPLQELYNPIQLELSNTAVL HQMRRDQVTDTCRANSATSR KRRVLTPNDLKHLVVDEDHE LIYCYVPKVACTNWKRLMMV LTGRGKYSDPMEIPANEAHV SANLKTLNQYSIPEINHRLK SYMKFLFVREPFERLVSAYR NKFTQKYNISFHKRYGTKII KRQRKNATQEALRKGDDVKF EEFVAYLIDPHTQREEPFNE HWQTVYSLCHPCHIHYDLV |
| Tissue Specificity | Widely expressed. Highly expressed in spleen, thymus, bone marrow, peripheral blood leukocytes, lymph node, heart, brain, lung and placenta. |
| Post Translational Modifications | N-glycosylated.required for activity and stability. |
| Function | Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor. |
| Protein Name | Carbohydrate Sulfotransferase 11Chondroitin 4-O-Sulfotransferase 1Chondroitin 4-Sulfotransferase 1C4s-1C4st-1C4st1 |
| Database Links | Reactome: R-HSA-2022870 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Carbohydrate Sulfotransferase 11 antibodyAnti-Chondroitin 4-O-Sulfotransferase 1 antibodyAnti-Chondroitin 4-Sulfotransferase 1 antibodyAnti-C4s-1 antibodyAnti-C4st-1 antibodyAnti-C4st1 antibodyAnti-CHST11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
