| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CEP120 (1-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CEP120 |
| Gene ID: |
153241 |
| Uniprot ID: |
CE120_HUMAN |
| Immunogen Region: |
1-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CEP120 (NP_694955.2). |
| Immunogen Sequence: |
MVSKSDQLLIVVSILEGRHF PKRPKHMLVVEAKFDGEQLA TDPVDHTDQPEFATELAWEI DRKALHQHRLQRTPIKLQCF ALDPVTSAKETIGYIVLDLR TAQETKQAPKWYQLLSNKYT KFKSEIQISIALETDTKPPV DSFKAKGAPPRDGKVPAILA GLDPRDIVAVLNEEGGYHQI GPAEYCTDSFIMSVTIAFAT QLEQLIPCTMKLPERQPEFF FYYSLLGNDVTNEPFNDLI |
| Function | Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner. |
| Protein Name | Centrosomal Protein Of 120 KdaCep120Coiled-Coil Domain-Containing Protein 100 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeRegulates The Localization Of Tacc3 To The Centrosome In Neural Progenitors In Vivo |
| Alternative Antibody Names | Anti-Centrosomal Protein Of 120 Kda antibodyAnti-Cep120 antibodyAnti-Coiled-Coil Domain-Containing Protein 100 antibodyAnti-CEP120 antibodyAnti-CCDC100 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
