| Host: | Rabbit |
| Applications: | IHC/ELISA |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Adenosine Deaminase 2 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: | Antigen affinity purification |
| Concentration: | 0.7 mg/mL |
| Dilution Range: | IHC 1:30-1:150 |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | ADA2 |
| Gene ID: | 51816 |
| Uniprot ID: | ADA2_HUMAN |
| Immunogen: | Fusion protein of human CECR1 |
| Tissue Specificity | Detected in blood plasma (at protein level). Widely expressed, with most abundant expression in human adult heart, lung, lymphoblasts, and placenta as well as fetal lung, liver, and kidney. In embryo, expressed in the outflow tract and atrium of the developing heart, the VII/VIII cranial nerve ganglion, and the notochord. |
| Function | Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity. |
| Protein Name | Adenosine Deaminase 2 Cat Eye Syndrome Critical Region Protein 1 |
| Database Links | Reactome: R-HSA-5683826 Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Adenosine Deaminase 2 antibody Anti-Cat Eye Syndrome Critical Region Protein 1 antibody Anti-ADA2 antibody Anti-ADGF antibody Anti-CECR1 antibody Anti-IDGFL antibody |
Information sourced from Uniprot.org